T helper cell dysregulation with hepatitis B and rebalance with glucocorticoids
نویسندگان
چکیده
منابع مشابه
relationship between hbv genotypes b, c and follicular helper t cells in patients with chronic hepatitis b and its significance
background clinical observations have shown that patients infected with chronic hepatitis b virus (hbv) genotype c versus genotype b had a higher load of the virus, more serious illness, and poorer responses to antiviral therapy and prognosis. however, the disparity between the two has not been clarified. objectives to explore possible relationship between hbv genotypes b and c and peripheral b...
متن کاملRatios of T-helper 2 Cells to T-helper 1 Cells and Cytokine Levels in Patients with Hepatitis B
BACKGROUND Hepatitis B is an immune response-mediated disease. The aim of this study was to explore the differences of ratios of T-helper (Th) 2 cells to Th1 cells and cytokine levels in acute hepatitis B (AHB) patients and chronic hepatitis B virus (HBV)-infected patients in immune-tolerance and immune-active phases. METHODS Thirty chronic HBV-infected patients in the immune-tolerant phase (...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Differential macrophage requirements for T helper cell and T helper cell-induced B lymphocyte proliferation
Major histocompatibility complex-restricted helper T cell clones against "minor" antigens expressed on B cell and macrophage surfaces, when confronted with appropriate T cell-depleted spleen cells, are induced to proliferation and, in turn, activate "target-responder" B cells to polyclonal growth and maturation. Irradiation of helper cell populations, however, demonstrates that their effector f...
متن کاملLentivirally overexpressed T-bet regulates T-helper cell lineage commitment in chronic hepatitis B patients.
Chronic hepatitis B virus (HBV) infection is commonly considered to occur as a result of disturbance of the immune system. T-box expressed in T cells (T-bet) is an essential transcription factor for T helper (Th) cell differentiation and function. The aim of this study was to investigate the effect of T-bet overexpression on Th cell differentiation and the possible mechanism in chronic hepatiti...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i48.18354